{"id":187,"date":"2020-12-04T16:05:30","date_gmt":"2020-12-04T05:35:30","guid":{"rendered":"http:\/\/sites.flinders.edu.au\/precision-medicines-group\/?page_id=187"},"modified":"2021-02-03T15:49:53","modified_gmt":"2021-02-03T05:19:53","slug":"the-ev-biomarker-drug-metabolism-lab","status":"publish","type":"page","link":"https:\/\/sites.flinders.edu.au\/precision-medicine-group\/the-ev-biomarker-drug-metabolism-lab\/","title":{"rendered":"The EV Biomarker Discovery Lab"},"content":{"rendered":"<div class=\"wpb-content-wrapper\" id=\"wpb-content-root\"><p>[vc_row equal_height=&#8221;yes&#8221; content_placement=&#8221;middle&#8221; parallax=&#8221;content-moving&#8221; parallax_image=&#8221;35&#8243; parallax_speed_bg=&#8221;2.0&#8243; css=&#8221;.vc_custom_1607405582072{padding-top: 0px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;}&#8221;][vc_column][vc_empty_space height=&#8221;40&#8243;][vc_row_inner][vc_column_inner css=&#8221;.vc_custom_1607397184845{border-top-width: 40px !important;border-right-width: 40px !important;border-bottom-width: 30px !important;border-left-width: 40px !important;padding-top: 20px !important;padding-right: 20px !important;padding-bottom: 20px !important;padding-left: 20px !important;background-color: rgba(255,255,255,0.89) !important;*background-color: rgb(255,255,255) !important;}&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h1 style=\"text-align: center\"><strong>The EV Biomarker Discovery Lab<\/strong><\/h1>\n<p>[\/vc_column_text][vc_separator][\/vc_column_inner][\/vc_row_inner][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h4>Our lab is proud to undertaking novel, cutting-edge research in the field of exosome derived biomarkers of drug exposure. We are passionate about translating pharmacokinetic principles into clinical practice through the optimization of drug dosing with a specific interest in precision dosing of anti-cancer drugs to achieve optimal therapeutic outcomes for oncology patients.<\/h4>\n<p>[\/vc_column_text][vc_empty_space][vc_btn title=&#8221;View our latest research output&#8221; style=&#8221;gradient-custom&#8221; gradient_custom_color_1=&#8221;#ffd300&#8243; gradient_custom_color_2=&#8221;#ffd300&#8243; gradient_text_color=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;lg&#8221; align=&#8221;center&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fas fa-external-link-alt&#8221; css_animation=&#8221;fadeIn&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:https%3A%2F%2Fwww.researchgate.net%2Fproject%2FPrecision-medicine-for-targeted-anti-cancer-medicines|title:ResearchGate|target:_blank&#8221;][\/vc_column][\/vc_row][vc_row css=&#8221;.vc_custom_1607409739762{padding-top: 25px !important;padding-right: 25px !important;padding-bottom: 25px !important;padding-left: 25px !important;background-position: 0 0 !important;background-repeat: repeat !important;}&#8221;][vc_column][vc_empty_space][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;241&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h6 style=\"text-align: center\"><strong>Extracellular vesicle isolation and characterization<\/strong><\/h6>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243; css=&#8221;.vc_custom_1607409750892{border-top-width: 0px !important;border-right-width: 0px !important;border-bottom-width: 0px !important;border-left-width: 0px !important;padding-top: 0px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;}&#8221;][vc_single_image image=&#8221;237&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h6 style=\"text-align: center\"><strong>Physiologically based pharmacokinetic modelling<\/strong><\/h6>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;243&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h6 style=\"text-align: center\"><strong>GCP certified healthy volunteer trial design and conduct<\/strong><\/h6>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space][vc_row_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;239&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h6 style=\"text-align: center\"><strong>Nucleic acid (miRNA and mRNA) analysis<\/strong><\/h6>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;242&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h6 style=\"text-align: center\"><strong>LC-MS based protein and small-molecule quantification<\/strong><\/h6>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;240&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h6 style=\"text-align: center\"><strong>Biostatistics<\/strong><\/h6>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_empty_space][\/vc_column][\/vc_row][vc_section][vc_row][vc_column][vc_empty_space][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h1 style=\"text-align: center\">Our Team<\/h1>\n<p>[\/vc_column_text][vc_separator][\/vc_column][\/vc_row][\/vc_section][vc_row][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;94&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>A\/Prof Andrew Rowland<\/strong><\/h3>\n<h4 style=\"text-align: center\">Laboratory Lead<\/h4>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_btn title=&#8221;Profile&#8221; style=&#8221;outline-custom&#8221; outline_custom_color=&#8221;#011c2c&#8221; outline_custom_hover_background=&#8221;#ffd300&#8243; outline_custom_hover_text=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;xs&#8221; align=&#8221;left&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fas fa-external-link-alt&#8221; button_block=&#8221;true&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:https%3A%2F%2Fwww.flinders.edu.au%2Fpeople%2Fandrew.rowland|target:_blank&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_btn title=&#8221;Email&#8221; style=&#8221;outline-custom&#8221; outline_custom_color=&#8221;#011c2c&#8221; outline_custom_hover_background=&#8221;#ffd300&#8243; outline_custom_hover_text=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;xs&#8221; align=&#8221;left&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;far fa-envelope&#8221; button_block=&#8221;true&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:mailto%3Aandrew.rowland%40flinders.edu.au|target:_blank&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;92&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Professor Michael Sorich\u00a0<\/strong><\/h3>\n<h4 style=\"text-align: center\">Laboratory Lead<\/h4>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_btn title=&#8221;Profile&#8221; style=&#8221;outline-custom&#8221; outline_custom_color=&#8221;#011c2c&#8221; outline_custom_hover_background=&#8221;#ffd300&#8243; outline_custom_hover_text=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;xs&#8221; align=&#8221;left&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fas fa-external-link-alt&#8221; button_block=&#8221;true&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:https%3A%2F%2Fwww.flinders.edu.au%2Fpeople%2Fmichael.sorich|target:_blank&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_btn title=&#8221;Email&#8221; style=&#8221;outline-custom&#8221; outline_custom_color=&#8221;#011c2c&#8221; outline_custom_hover_background=&#8221;#ffd300&#8243; outline_custom_hover_text=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;xs&#8221; align=&#8221;left&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;far fa-envelope&#8221; button_block=&#8221;true&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:mailto%3Amichael.sorich%40flinders.edu.au|target:_blank&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;95&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Dr Ashley Hopkins\u00a0\u00a0<\/strong><\/h3>\n<h4 style=\"text-align: center\">Senior Research Fellow<\/h4>\n<p>[\/vc_column_text][vc_row_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_btn title=&#8221;Profile&#8221; style=&#8221;outline-custom&#8221; outline_custom_color=&#8221;#011c2c&#8221; outline_custom_hover_background=&#8221;#ffd300&#8243; outline_custom_hover_text=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;xs&#8221; align=&#8221;left&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;fas fa-external-link-alt&#8221; button_block=&#8221;true&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:https%3A%2F%2Fwww.flinders.edu.au%2Fpeople%2Fashley.hopkins|target:_blank&#8221;][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_btn title=&#8221;Email&#8221; style=&#8221;outline-custom&#8221; outline_custom_color=&#8221;#011c2c&#8221; outline_custom_hover_background=&#8221;#ffd300&#8243; outline_custom_hover_text=&#8221;#011c2c&#8221; shape=&#8221;square&#8221; size=&#8221;xs&#8221; align=&#8221;left&#8221; i_align=&#8221;right&#8221; i_icon_fontawesome=&#8221;far fa-envelope&#8221; button_block=&#8221;true&#8221; add_icon=&#8221;true&#8221; link=&#8221;url:mailto%3Aashley.hopkins%40flinders.edu.au|target:_blank&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row css_animation=&#8221;fadeIn&#8221;][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;31&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Dr Angela Rowland\u00a0<\/strong><\/h3>\n<h4 style=\"text-align: center\">Medical Practioner<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;234&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Dr Zivile Useckaite<\/strong><\/h3>\n<h4 style=\"text-align: center\">Research Fellow<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;97&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text]<\/p>\n<h3 style=\"text-align: center\"><strong>Lauren Newman<\/strong><\/h3>\n<h4 style=\"text-align: center\">Research Assistant<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;93&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text]<\/p>\n<h3 style=\"text-align: center\"><strong>Alia Fahmy<\/strong><\/h3>\n<h4 style=\"text-align: center\">PhD Candidate<\/h4>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;96&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text]<\/p>\n<h3 style=\"text-align: center\"><b>Asha Kapetas\u00a0<\/b><\/h3>\n<h4 style=\"text-align: center\">Research Assistant<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;31&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Radwan Ansaar<\/strong><\/h3>\n<h4 style=\"text-align: center\">PhD Candidate<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;303&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Elise Newman<\/strong><\/h3>\n<h4 style=\"text-align: center\">MD Advanced Studies Student<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;305&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Kennith Wills<\/strong><\/h3>\n<h4 style=\"text-align: center\">MD Advanced Studies Student<\/h4>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;306&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Stephen Behan<\/strong><\/h3>\n<h4 style=\"text-align: center\">MD Advanced Studies Student<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;294&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Nuy Chau<\/strong><\/h3>\n<h4 style=\"text-align: center\">Research Assistant<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][\/vc_column][vc_column width=&#8221;1\/4&#8243;][\/vc_column][\/vc_row][vc_row css_animation=&#8221;fadeIn&#8221;][vc_column][vc_empty_space][vc_column_text]<\/p>\n<h1 style=\"text-align: center\">Collaborators<\/h1>\n<p>[\/vc_column_text][vc_separator css_animation=&#8221;fadeIn&#8221;][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;295&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>A David Rodrigues<\/strong><\/h3>\n<h4 style=\"text-align: center\">Transporter Science<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;296&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Jean-Claude Marshall <\/strong><\/h3>\n<h4 style=\"text-align: center\">Precision Medicine<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;289&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Jillian Johnson <\/strong><\/h3>\n<h4 style=\"text-align: center\">Clinical Pharmacogenomics<\/h4>\n<h4 style=\"text-align: center\"><\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;292&#8243; img_size=&#8221;300&#215;300&#8243; alignment=&#8221;center&#8221; css_animation=&#8221;fadeIn&#8221;][vc_column_text css_animation=&#8221;fadeIn&#8221;]<\/p>\n<h3 style=\"text-align: center\"><strong>Hendrik Neubert <\/strong><\/h3>\n<h4 style=\"text-align: center\">Biomedicine Design<\/h4>\n<p>[\/vc_column_text][\/vc_column][vc_column][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;293&#8243; 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